Scan your resume against ATS criteria for this Sr. Bioinformatics Scientist role at Veracyte.
At Veracyte, we offer exciting career opportunities for those interested in joining a pioneering team that is committed to transforming cancer care for patients across the globe. Working at Veracyte enables our employees to not make a meaningful impact on the lives of patients, but to also learn and grow within a purpose driven environment. This is what we call the Veracyte way – it’s about how we work together, guided by our values, to give clinicians the insights they need to help patients make life-changing decisions
We are seeking an experienced and motivated Bioinformatics Scientist to join our Bioinformatics and Data Science Team focused on developing regulated diagnostics products. The ideal candidate will bring deep expertise in NGS technologies with a strong understanding of regulatory environments including CAP/CLIA and IVD product development. The successful candidate will play a crucial role in designing, developing, and optimizing our next generation of genomic assays. This position requires a unique blend of expertise in bioinformatics, extensive experience in assay optimization, analytical validation, strong skills in analytical pipeline development, automation and optimization, a deep understanding of molecular biology, and a passion for transforming complex biological data into actionable insights
Apply leading edge knowledge in bioinformatics, genomics, and assay technologies, to contribute to development of company's concepts and principles and to achieve assay development objectives in creative and effective ways.
Drive development study design and all analysis for assay development effort in collaboration with cross-functional teams.
Develop statistical and machine learning techniques to comprehensively evaluate assay performance and create optimization strategies.
Communicate analysis results, methodologies, and scientific findings to internal teams, external collaborators, and stakeholders.
Develop scalable, production-grade workflows for high-throughput NGS data analysis using AWS and containerized environments.
Facilitate successful production pipeline deployment by working closely with infrastructure and engineering teams
Ensure compliance with regulatory standards (CAP/CLIA, FDA, IVDR) throughout the bioinformatics development lifecycle, including rigorous testing and documentation.
Contribute to regulatory submissions and audits by providing technical documentation and validation reports.
Provide scientific guidance and mentorship to junior bioinformatics team members.
REQUIRED EXPERIENCE:
PhD or MS in bioinformatics, computational biology, or an adjacent data science field, such as biostatistics, statistics or computer science.
Proven experience - A minimum of 6 -7 years of experience in bioinformatics analysis, algorithm development, and pipeline implementation.
Thorough understanding of NGS technologies and various methods for library preparation (WGS, enrichment, RNA-Seq, methylation, etc.).
Proficiency in quantitative transcriptomics from NGS or expression microarray data in human disease/biology specifically, such as differential expression, dimension reduction, expression-based classifier development, RNA-based signatures, cell type deconvolution.
Proficiency in machine learning, development of novel bioinformatics methodologies, and algorithms development, including benchmarking of computational methods.
Proven experience developing and deploying bioinformatics workflows in AWS (e.g., EC2, S3, Step Functions, Batch, Lambda, etc.).
Strong proficiency in Python, including experience with testing frameworks and SDLC best practices.
Close collaboration with Quality and Regulatory Affairs team on assay and analysis pipeline development and verification.
Demonstrated record of technical and scientific leadership, ownership, and independent work.
RELEVANT EXPERIENCE (preferred but not required):
Track record of working with wet lab scientists on iterative experiment design, execution, analysis, and interpretation as a tightly integrated team.
Proficiency in genomics, sequence analysis, and secondary analysis, such as variant calling (e.g., SNVs/MNVs/indels, CNV, structural variants), NGS QC, splicing, circular nucleic acids.
Strong understanding of germline and somatic mutation processes leading to complex variation and genome-wide biomarkers with potential clinical utility, such as TMB, mutational signatures, LOH.
Working knowledge of R.
Experience with relational and non-relational database technologies is a plus.
Excellent communicator about complex technical topics in an interdisciplinary setting, especially by using data visualizations and diagrams.
Excellent technical problem solving and troubleshooting skills
#LI-Hybrid, or #LI-Remote
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The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to years of experience, skillset, geographic location, industry, education, etc. Base pay is part of the Total Package that is provided to compensate and recognize employees for their work, and this role may be eligible for additional discretionary bonuses/incentives, and restricted stock units.
Pay range$150,000—$189,000 USD
Veracyte is a growing company that offers significant career opportunities if you are curious, driven, patient-oriented and aspire to help us build a great company. We offer competitive compensation and benefits, and are committed to fostering an inclusive workforce, where diverse backgrounds are represented, engaged, and empowered to drive innovative ideas and decisions. We are thrilled to be recognized as a 2024 Certified™ Great Place to Work® in both the US and Israel - a testament to our dynamic, inclusive, and inspiring workplace where passion meets purpose.
Veracyte (Nasdaq: VCYT) is a global diagnostics company whose vision is to transform cancer care for patients all over the world. We empower clinicians with the high-value insights they need to guide and assure patients at pivotal moments in the race to diagnose and treat cancer. Our Veracyte Diagnostics Platform delivers high-performing cancer tests that are fueled by broad genomic and clinical data, deep bioinformatic and AI capabilities, and a powerful evidence-generation engine, which ultimately drives durable reimbursement and guideline inclusion for our tests, along with new insights to support continued innovation and pipeline development. For more information, please visit https://cts.businesswire.com/ct/CT?id=smartlink&url=https%3A%2F%2Fwww.veracyte.com%2F&esheet=54340020&newsitemid=20251015446872&lan=en-US&anchor=www.veracyte.com&index=5&md5=4d48386b00ece1531372e2e593d7cd2d www.veracyte.com or follow us on https://cts.businesswire.com/ct/CT?id=smartlink&url=https%3A%2F%2Fwww.linkedin.com%2Fcompany%2Fveracyte%2F&esheet=54340020&newsitemid=20251015446872&lan=en-US&anchor=LinkedIn&index=6&md5=234cba826cb637f449d2722139f551ef LinkedIn or https://cts.businesswire.com/ct/CT?id=smartlink&url=https%3A%2F%2Fx.com%2Fveracyte%3Fs%3D11&esheet=54340020&newsitemid=20251015446872&lan=en-US&anchor=X+%28Twitter%29&index=7&md5=20ead95735af622bf261b20735515b66 X (Twitter).
Veracyte, Inc. is an Equal Opportunity Employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status or disability status. Veracyte participates in E-Verify in the United States. View our https://www.veracyte.com/legal/privacy-statement-for-california-residents/ CCPA Disclosure Notice
ptomics from NGS or expression microarray data in human disease/biology specifically, such as differential expression, dimension reduction, expression-based classifier development, RNA-based signatures, cell type deconvolution.
How to apply for Sr. Bioinformatics Scientist at Veracyte?
Click the "Apply on Company Website" button on this page to submit your application directly on the employer's official portal.
What is the salary for this role?
The salary for this role is $160,000 - $180,000 per annum.
What experience is required?
6-7 years of experience is required.
Is this position still open?
Yes, currently active and accepting applications.
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Sr. Bioinformatics Scientist
Veracyte · Remote ; South San Francisco